Wiskott Aldrich Syndrome is a disorder which causes when there is a mutation in the gene which is known as the WAS Gene. This is mainly an immune deficiency disorder that is mostly seen in children. This starts to appear in an early stage and it continues till adulthood at times. Since this is an issue related to the genetics, it can be carried forward to the next generation. Genetic problems are such that does not have a specific reason for the inception. Once it starts, it may go on.

The main cause for this is the immune disorder. The effects of WAS is that most of the patient produce very little T and B cells which is very important for the body. When there is mutation in any of the genes then Wiskott Aldrich Syndrome is noticed. A gene is the essential part of the body, which decides the cell formation and growth of the body. The mutation, which is caused in the gene, affects the X chromosome of the male. The female has two X chromosomes where the mutation does not really take place.

Wiskott Aldrich Syndrome

The female may not have the mutated gene but she can still be the carrier of the mutated gene. She can also pass this gene to her children and this is how it gets transferred to generations. There is basically no such specific cause for which this mutation might take place but once it starts it can be passed on from one generation to the other.

The mutation of the WAS gene affects mainly the WAS protein which in turn affects the B and T cells. This is when the platelet count decreases and all the symptoms start showing up. The symptoms may include bleeding and bruises, eczema, ashes all over the body, very dry skin and also infections. When there is a mutation in these WAS genes then the cells stop multiplying and thus the immune system remains very weak. Wiskott Aldrich Syndrome can be fatal at times, if it is not treated from an early stage. If the problem persists till adulthood, then this disorder may pass on to the next generation and mainly the male member is affected. The mutation of the X chromosome in male genes causes WAS. Make sure when you notice the symptoms, start the treatment as early as possible so that the condition can be made less severe.